|
KMID : 0359920110300010094
|
|
Korean Journal of Nephrology
2011 Volume.30 No. 1 p.94 ~ p.97
|
|
|
A Case of Adult Minimal Change Nephrotic Syndrome Associated with Thin Basement Membrane Nephropathy
|
|
Song Ji-Eun
Kim Ki-Hoe
Kim Jeong-Gwan
Park Sung-Hyun
Oh Wang-Guk
Moon Kyung-Chul
Kim Jeong-Hwa
Lee Kwang-Yeong
|
|
|
Abstract
|
|
|
|
Thin basement membrane nephropathy (TBMN) is characterized by persistent hematuria, mild proteinuria, normal renal function and family history of hematuria. Many studies report that TBMN commonly occurs together with other glomerular diseases such as minimal change nephrotic syndrome, membranous nephropathy, IgA nephropathy and focal segmental glomerulosclerosis. Especially, the case of TBMN with minimal change nephrotic syndrome has been rare. We report a case of adult minimal change nephrotic syndrome with TBMN in a 44-year-old female with general edema and microscopic hematuria. On renal biopsy, electron microscopic examination demonstrated diffuse thinning of glomerular basement membrane with the thickness less than 250nm and diffuse foot process effacement. Treatment with corticosteroid resulted in complete remission of proteinuria.
|
|
|
KEYWORD
|
|
|
Minimal change nephrotic syndrome, Glomerular basement membrane, Hematuria
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|